ALNYLAM PHARMACEUTICALS, INC. Financial Summary

Quick Answer

ALNYLAM PHARMACEUTICALS, INC. reported Total Revenue of $3.71 billion for fiscal year 2025.

ALNYLAM PHARMACEUTICALS, INC. — Key Financials by Year

Metric 2025 2024 2023 2022 2021 2020
Total Revenue $3.71B
+65.2%
$2.25B
+23.0%
$1.83B
+76.2%
$1.04B
+22.9%
$844.29M
+71.3%
$492.85M
+124.3%
Revenue (ASC 606) $3.71B
+65.2%
$2.25B
+23.0%
$1.83B
+76.2%
$1.04B
+22.9%
$844.29M
+71.3%
$492.85M
+124.3%
Net Income $313.75M
+212.8%
-$278.16M
+36.8%
-$440.24M
+61.1%
-$1.13B
-32.6%
-$852.82M
+0.6%
-$858.28M
+3.1%
Diluted EPS $2.33
+206.9%
-$2.18
+38.1%
-$3.52
+62.2%
-$9.30
-29.2%
-$7.20
+3.5%
-$7.46
+8.0%
Total Assets $4.97B
+17.1%
$4.24B
+10.7%
$3.83B
+8.0%
$3.55B
-2.7%
$3.64B
+6.9%
$3.41B
+42.2%
Cash and Equivalents $1.66B
+71.5%
$966.43M
+18.9%
$812.69M
-6.2%
$866.39M
+5.7%
$819.98M
+65.1%
$496.58M
-9.2%
Stockholders Equity $789.18M
+1076.3%
$67.09M
+130.4%
-$220.64M
-39.5%
-$158.22M
-126.9%
$588.20M
-42.1%
$1.02B
-29.4%
R&D Expense $1.32B
+17.2%
$1.13B
+12.1%
$1.00B
+13.7%
$883.01M
+11.5%
$792.16M
+21.0%
$654.82M
-0.0%
Operating Income $501.58M
+383.6%
-$176.88M
+37.3%
-$282.18M
+64.1%
-$785.07M
-10.8%
-$708.65M
+14.5%
-$828.44M
+11.8%
Shares Outstanding 132.38M
+2.4%
129.29M
+2.8%
125.79M
+1.5%
123.92M
+3.1%
120.18M
+3.2%
116.43M
+3.8%

Most Recent Quarter

Metric Quarter Ending Value YoY QoQ
Total Revenue September 30, 2025 $1.25B +149.3% +61.4%
Revenue (ASC 606) September 30, 2025 $1.25B +149.3% +61.4%
Net Income September 30, 2025 $251.08M +325.0% +478.8%
Diluted EPS September 30, 2025 $1.84 +311.5% +460.8%
Total Assets September 30, 2025 $4.85B +15.4% +6.3%
Cash and Equivalents September 30, 2025 $1.49B +35.5% +33.8%
Long-Term Debt June 30, 2022 $677.72M +56.5% +0.1%
Stockholders Equity September 30, 2025 $233.89M +622.9% -6.7%
R&D Expense September 30, 2025 $358.81M +32.4% +10.9%
Operating Income September 30, 2025 $367.98M +578.5% +2371.6%
Shares Outstanding September 30, 2025 131.79M +2.3% +0.6%
  • ALNYLAM PHARMACEUTICALS, INC. reported Total Revenue of $3.71 billion for fiscal year 2025.
  • ALNYLAM PHARMACEUTICALS, INC. showed an increase of +65.2% in Total Revenue compared to the prior fiscal year.
  • ALNYLAM PHARMACEUTICALS, INC. reported Revenue (ASC 606) of $3.71 billion for fiscal year 2025.
  • ALNYLAM PHARMACEUTICALS, INC. showed an increase of +65.2% in Revenue (ASC 606) compared to the prior fiscal year.
  • ALNYLAM PHARMACEUTICALS, INC. reported Net Income of $313.75 million for fiscal year 2025.
  • ALNYLAM PHARMACEUTICALS, INC. showed an increase of +212.8% in Net Income compared to the prior fiscal year.
  • ALNYLAM PHARMACEUTICALS, INC. reported Diluted EPS of $2.33 per share for fiscal year 2025.
  • ALNYLAM PHARMACEUTICALS, INC. showed an increase of +206.9% in Diluted EPS compared to the prior fiscal year.
  • ALNYLAM PHARMACEUTICALS, INC. reported Total Assets of $4.97 billion for fiscal year 2025.
  • ALNYLAM PHARMACEUTICALS, INC. showed an increase of +17.1% in Total Assets compared to the prior fiscal year.
  • ALNYLAM PHARMACEUTICALS, INC. reported Cash and Equivalents of $1.66 billion for fiscal year 2025.
  • ALNYLAM PHARMACEUTICALS, INC. showed an increase of +71.5% in Cash and Equivalents compared to the prior fiscal year.
  • ALNYLAM PHARMACEUTICALS, INC. reported Stockholders Equity of $789.18 million for fiscal year 2025.
  • ALNYLAM PHARMACEUTICALS, INC. showed an increase of +1076.3% in Stockholders Equity compared to the prior fiscal year.
  • ALNYLAM PHARMACEUTICALS, INC. reported R&D Expense of $1.32 billion for fiscal year 2025.
  • ALNYLAM PHARMACEUTICALS, INC. showed an increase of +17.2% in R&D Expense compared to the prior fiscal year.
  • ALNYLAM PHARMACEUTICALS, INC. reported Operating Income of $501.58 million for fiscal year 2025.
  • ALNYLAM PHARMACEUTICALS, INC. showed an increase of +383.6% in Operating Income compared to the prior fiscal year.
  • ALNYLAM PHARMACEUTICALS, INC. reported Shares Outstanding of 132.38 million shares for fiscal year 2025.
  • ALNYLAM PHARMACEUTICALS, INC. showed an increase of +2.4% in Shares Outstanding compared to the prior fiscal year.
  • All figures are sourced from SEC EDGAR XBRL filings, last verified June 17, 2026.

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