Axsome Therapeutics, Inc. Financial Summary

Quick Answer

Axsome Therapeutics, Inc. reported Total Revenue of $638.50 million for fiscal year 2025.

Axsome Therapeutics, Inc. — Key Financials by Year

Metric 2025 2024 2023 2022 2021 2020
Total Revenue $638.50M
+65.5%
$385.69M
+42.5%
$270.60M
+440.8%
$50.04M
Revenue (ASC 606) $638.50M
+65.5%
$385.69M
+42.5%
$270.60M
+440.8%
$50.04M
Net Income -$183.17M
+36.2%
-$287.22M
-20.1%
-$239.24M
-27.8%
-$187.13M
-43.5%
-$130.40M
-26.7%
-$102.90M
-50.6%
Diluted EPS -$3.68
+38.6%
-$5.99
-13.7%
-$5.27
-14.6%
-$4.60
-32.6%
-$3.47
-25.3%
-$2.77
Total Assets $689.80M
+21.3%
$568.50M
-3.4%
$588.24M
+77.5%
$331.48M
+277.6%
$87.79M
-52.8%
$186.13M
-15.6%
Cash and Equivalents $322.93M
+2.4%
$315.35M
-18.3%
$386.19M
+92.3%
$200.84M
+132.3%
$86.47M
-53.0%
$183.88M
-16.4%
Long-Term Debt $117.75M
-34.8%
$180.71M
+1.5%
$178.07M
+88.9%
$94.26M
+92.0%
$49.09M
+1.6%
$48.32M
+178.8%
Stockholders Equity $88.30M
+54.9%
$57.02M
-70.1%
$190.98M
+74.3%
$109.56M
+600.9%
$15.63M
-86.3%
$113.79M
-36.3%
R&D Expense $183.28M
-2.0%
$187.08M
+91.0%
$97.94M
+69.0%
$57.95M
-0.2%
$58.06M
-17.3%
$70.24M
+30.9%
Operating Income -$166.76M
+40.6%
-$280.56M
-21.0%
-$231.82M
-28.9%
-$179.80M
-44.2%
-$124.71M
-25.8%
-$99.14M
-47.4%
Shares Outstanding 50.88M
+4.6%
48.67M
+2.8%
47.35M
+8.9%
43.50M
+15.0%
37.82M
+1.2%
37.37M
+1.2%

Most Recent Quarter

Metric Quarter Ending Value YoY QoQ
Total Revenue September 30, 2025 $170.99M +63.2% +14.0%
Revenue (ASC 606) September 30, 2025 $170.99M +63.2% +14.0%
Net Income September 30, 2025 -$47.23M +26.9% +1.6%
Diluted EPS September 30, 2025 -$0.94 +29.9% +3.1%
Total Assets September 30, 2025 $669.25M +19.2% +4.6%
Cash and Equivalents September 30, 2025 $325.27M -0.6% +7.3%
Long-Term Debt September 30, 2025 $117.64M -34.6% +0.1%
Stockholders Equity September 30, 2025 $73.73M -20.6% +0.9%
R&D Expense September 30, 2025 $40.16M -11.5% -18.9%
Operating Income September 30, 2025 -$46.11M +26.4% -25.6%
Shares Outstanding September 30, 2025 50.31M +3.9% +1.0%
  • Axsome Therapeutics, Inc. reported Total Revenue of $638.50 million for fiscal year 2025.
  • Axsome Therapeutics, Inc. showed an increase of +65.5% in Total Revenue compared to the prior fiscal year.
  • Axsome Therapeutics, Inc. reported Revenue (ASC 606) of $638.50 million for fiscal year 2025.
  • Axsome Therapeutics, Inc. showed an increase of +65.5% in Revenue (ASC 606) compared to the prior fiscal year.
  • Axsome Therapeutics, Inc. reported Net Income of -$183.17 million for fiscal year 2025.
  • Axsome Therapeutics, Inc. showed an increase of +36.2% in Net Income compared to the prior fiscal year.
  • Axsome Therapeutics, Inc. reported Diluted EPS of $3.68 per share (loss) for fiscal year 2025.
  • Axsome Therapeutics, Inc. showed an increase of +38.6% in Diluted EPS compared to the prior fiscal year.
  • Axsome Therapeutics, Inc. reported Total Assets of $689.80 million for fiscal year 2025.
  • Axsome Therapeutics, Inc. showed an increase of +21.3% in Total Assets compared to the prior fiscal year.
  • Axsome Therapeutics, Inc. reported Cash and Equivalents of $322.93 million for fiscal year 2025.
  • Axsome Therapeutics, Inc. showed an increase of +2.4% in Cash and Equivalents compared to the prior fiscal year.
  • Axsome Therapeutics, Inc. reported Long-Term Debt of $117.75 million for fiscal year 2025.
  • Axsome Therapeutics, Inc. showed a decrease of -34.8% in Long-Term Debt compared to the prior fiscal year.
  • Axsome Therapeutics, Inc. reported Stockholders Equity of $88.30 million for fiscal year 2025.
  • Axsome Therapeutics, Inc. showed an increase of +54.9% in Stockholders Equity compared to the prior fiscal year.
  • Axsome Therapeutics, Inc. reported R&D Expense of $183.28 million for fiscal year 2025.
  • Axsome Therapeutics, Inc. showed a decrease of -2.0% in R&D Expense compared to the prior fiscal year.
  • Axsome Therapeutics, Inc. reported Operating Income of -$166.76 million for fiscal year 2025.
  • Axsome Therapeutics, Inc. showed an increase of +40.6% in Operating Income compared to the prior fiscal year.
  • Axsome Therapeutics, Inc. reported Shares Outstanding of 50.88 million shares for fiscal year 2025.
  • Axsome Therapeutics, Inc. showed an increase of +4.6% in Shares Outstanding compared to the prior fiscal year.
  • All figures are sourced from SEC EDGAR XBRL filings, last verified June 17, 2026.

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