Denali Therapeutics Inc. Financial Summary

Quick Answer

Denali Therapeutics Inc. reported Total Revenue of $0.00 for fiscal year 2025.

Denali Therapeutics Inc. — Key Financials by Year

Metric 2025 2024 2023 2022 2021 2020
Total Revenue $0.00 $0.00
-100.0%
$330.53M
+204.7%
$108.46M
+122.9%
$48.66M
-85.5%
$335.66M
+1158.2%
Revenue (ASC 606) $0.00 $0.00
-100.0%
$330.53M
+214.6%
$105.06M
+115.9%
$48.66M
-85.5%
$335.56M
+1174.9%
Net Income -$512.54M
-21.2%
-$422.77M
-191.1%
-$145.22M
+55.5%
-$325.99M
-12.2%
-$290.58M
-508.5%
$71.14M
+136.0%
Diluted EPS -$2.97
-15.6%
-$2.57
-142.5%
-$1.06
+59.2%
-$2.60
-8.8%
-$2.39
-479.4%
$0.63
+130.4%
Total Assets $1.14B
-16.7%
$1.37B
+19.1%
$1.15B
-21.0%
$1.46B
+4.0%
$1.40B
-12.5%
$1.60B
+190.0%
Cash and Equivalents $205.33M
+17.4%
$174.96M
+37.6%
$127.11M
-41.7%
$218.04M
-25.7%
$293.48M
-42.1%
$507.14M
+538.3%
Stockholders Equity $1.01B
-17.6%
$1.23B
+19.3%
$1.03B
-1.1%
$1.04B
+8.3%
$962.29M
-16.4%
$1.15B
+191.4%
R&D Expense $418.78M
+5.6%
$396.44M
-6.5%
$423.88M
+18.2%
$358.73M
+35.2%
$265.35M
+24.8%
$212.62M
+9.9%
Operating Income -$555.34M
-14.0%
-$487.34M
-147.8%
-$196.70M
+42.3%
-$340.74M
-15.2%
-$295.75M
-571.6%
$62.72M
+129.4%
Shares Outstanding 156.18M
+8.3%
144.22M
+4.2%
138.39M
+1.8%
135.97M
+11.2%
122.28M
+1.5%
120.53M
+25.3%

Most Recent Quarter

Metric Quarter Ending Value YoY QoQ
Total Revenue September 30, 2024 $0.00 -100.0%
Revenue (ASC 606) September 30, 2024 $0.00 -100.0%
Net Income September 30, 2025 -$126.90M -18.4% -2.2%
Diluted EPS September 30, 2025 -$0.74 -17.5% -2.8%
Total Assets September 30, 2025 $1.06B -27.4% -9.5%
Cash and Equivalents September 30, 2025 $90.96M +0.4% -35.6%
Stockholders Equity September 30, 2025 $926.20M -29.8% -9.8%
R&D Expense September 30, 2025 $101.95M +3.8% -0.7%
Operating Income September 30, 2025 -$137.43M -11.6% -1.8%
Shares Outstanding September 30, 2025 146.63M +1.9% +0.6%
  • Denali Therapeutics Inc. reported Total Revenue of $0.00 for fiscal year 2025.
  • Denali Therapeutics Inc. reported Revenue (ASC 606) of $0.00 for fiscal year 2025.
  • Denali Therapeutics Inc. reported Net Income of -$512.54 million for fiscal year 2025.
  • Denali Therapeutics Inc. showed a decrease of -21.2% in Net Income compared to the prior fiscal year.
  • Denali Therapeutics Inc. reported Diluted EPS of $2.97 per share (loss) for fiscal year 2025.
  • Denali Therapeutics Inc. showed a decrease of -15.6% in Diluted EPS compared to the prior fiscal year.
  • Denali Therapeutics Inc. reported Total Assets of $1.14 billion for fiscal year 2025.
  • Denali Therapeutics Inc. showed a decrease of -16.7% in Total Assets compared to the prior fiscal year.
  • Denali Therapeutics Inc. reported Cash and Equivalents of $205.33 million for fiscal year 2025.
  • Denali Therapeutics Inc. showed an increase of +17.4% in Cash and Equivalents compared to the prior fiscal year.
  • Denali Therapeutics Inc. reported Stockholders Equity of $1.01 billion for fiscal year 2025.
  • Denali Therapeutics Inc. showed a decrease of -17.6% in Stockholders Equity compared to the prior fiscal year.
  • Denali Therapeutics Inc. reported R&D Expense of $418.78 million for fiscal year 2025.
  • Denali Therapeutics Inc. showed an increase of +5.6% in R&D Expense compared to the prior fiscal year.
  • Denali Therapeutics Inc. reported Operating Income of -$555.34 million for fiscal year 2025.
  • Denali Therapeutics Inc. showed a decrease of -14.0% in Operating Income compared to the prior fiscal year.
  • Denali Therapeutics Inc. reported Shares Outstanding of 156.18 million shares for fiscal year 2025.
  • Denali Therapeutics Inc. showed an increase of +8.3% in Shares Outstanding compared to the prior fiscal year.
  • All figures are sourced from SEC EDGAR XBRL filings, last verified June 17, 2026.

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