Lyra Therapeutics, Inc. Financial Summary

Quick Answer

Lyra Therapeutics, Inc. reported Total Revenue of $398.0 thousand for fiscal year 2025.

Lyra Therapeutics, Inc. — Key Financials by Year

Metric 2025 2024 2023 2022 2021 2020
Total Revenue $398.0K
-74.1%
$1.53M
-1.5%
$1.56M
+14.3%
$1.36M
+378.2%
$285.0K
Revenue (ASC 606) $398.0K
-74.1%
$1.53M
-1.5%
$1.56M
+14.3%
$1.36M
+378.2%
$285.0K
Net Income -$28.92M
+69.0%
-$93.44M
-49.1%
-$62.68M
-13.4%
-$55.28M
-27.0%
-$43.51M
-96.7%
-$22.13M
-35.7%
Diluted EPS -$18.62
+74.0%
-$71.75
-5594.4%
-$1.26
+31.1%
-$1.83
+45.4%
-$3.35
Total Assets $36.11M
-45.6%
$66.35M
-53.5%
$142.60M
+29.7%
$109.97M
+100.4%
$54.87M
-32.1%
$80.83M
+440.2%
Cash and Equivalents $15.89M
-60.8%
$40.58M
+81.5%
$22.35M
-31.3%
$32.55M
-28.8%
$45.75M
-38.7%
$74.59M
+660.5%
Stockholders Equity -$10.72M
-192.4%
$11.59M
-87.0%
$89.42M
+10.7%
$80.75M
+135.3%
$34.32M
-53.9%
$74.49M
+160.4%
R&D Expense $18.41M
-57.9%
$43.77M
-8.9%
$48.03M
+23.8%
$38.80M
+30.7%
$29.69M
+137.1%
$12.52M
+4.1%
Operating Income -$31.02M
+67.8%
-$96.35M
-43.5%
-$67.12M
-19.2%
-$56.31M
-29.1%
-$43.62M
-96.4%
-$22.21M
-34.4%
Shares Outstanding 1.77M
+35.5%
1.31M
-97.7%
57.21M
+79.8%
31.83M
+144.7%
13.01M
+0.6%
12.93M
+5501.8%

Most Recent Quarter

Metric Quarter Ending Value YoY QoQ
Total Revenue September 30, 2025 $25.0K -87.2% -86.3%
Revenue (ASC 606) September 30, 2025 $25.0K -87.2% -86.3%
Net Income September 30, 2025 -$5.98M +49.6% +19.5%
Diluted EPS September 30, 2025 -$3.38 +62.7% +38.7%
Total Assets September 30, 2025 $43.71M -44.5% -16.9%
Cash and Equivalents September 30, 2025 $22.05M -7.3% -26.0%
Stockholders Equity September 30, 2025 -$4.33M -121.0% -366.8%
R&D Expense September 30, 2025 $4.05M -31.4% -20.8%
Operating Income September 30, 2025 -$6.24M +49.9% +29.3%
Shares Outstanding September 30, 2025 1.64M -97.5% +1.2%
  • Lyra Therapeutics, Inc. reported Total Revenue of $398.0 thousand for fiscal year 2025.
  • Lyra Therapeutics, Inc. showed a decrease of -74.1% in Total Revenue compared to the prior fiscal year.
  • Lyra Therapeutics, Inc. reported Revenue (ASC 606) of $398.0 thousand for fiscal year 2025.
  • Lyra Therapeutics, Inc. showed a decrease of -74.1% in Revenue (ASC 606) compared to the prior fiscal year.
  • Lyra Therapeutics, Inc. reported Net Income of -$28.92 million for fiscal year 2025.
  • Lyra Therapeutics, Inc. showed an increase of +69.0% in Net Income compared to the prior fiscal year.
  • Lyra Therapeutics, Inc. reported Diluted EPS of $18.62 per share (loss) for fiscal year 2025.
  • Lyra Therapeutics, Inc. showed an increase of +74.0% in Diluted EPS compared to the prior fiscal year.
  • Lyra Therapeutics, Inc. reported Total Assets of $36.11 million for fiscal year 2025.
  • Lyra Therapeutics, Inc. showed a decrease of -45.6% in Total Assets compared to the prior fiscal year.
  • Lyra Therapeutics, Inc. reported Cash and Equivalents of $15.89 million for fiscal year 2025.
  • Lyra Therapeutics, Inc. showed a decrease of -60.8% in Cash and Equivalents compared to the prior fiscal year.
  • Lyra Therapeutics, Inc. reported Stockholders Equity of -$10.72 million for fiscal year 2025.
  • Lyra Therapeutics, Inc. showed a decrease of -192.4% in Stockholders Equity compared to the prior fiscal year.
  • Lyra Therapeutics, Inc. reported R&D Expense of $18.41 million for fiscal year 2025.
  • Lyra Therapeutics, Inc. showed a decrease of -57.9% in R&D Expense compared to the prior fiscal year.
  • Lyra Therapeutics, Inc. reported Operating Income of -$31.02 million for fiscal year 2025.
  • Lyra Therapeutics, Inc. showed an increase of +67.8% in Operating Income compared to the prior fiscal year.
  • Lyra Therapeutics, Inc. reported Shares Outstanding of 1.77 million shares for fiscal year 2025.
  • Lyra Therapeutics, Inc. showed an increase of +35.5% in Shares Outstanding compared to the prior fiscal year.
  • All figures are sourced from SEC EDGAR XBRL filings, last verified June 17, 2026.

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