OnKure Therapeutics, Inc. Financial Summary

Quick Answer

OnKure Therapeutics, Inc. reported Net Income of -$59.52 million for fiscal year 2025.

OnKure Therapeutics, Inc. — Key Financials by Year

Metric 2025 2024 2023 2022 2021 2020
Net Income -$59.52M
-13.0%
-$52.67M
-49.2%
-$35.31M
+32.0%
-$51.95M
-30.6%
-$39.77M
-104.3%
-$19.46M
Diluted EPS -$4.40
+71.2%
-$15.28
+87.7%
-$124.41
-5768.4%
-$2.12
+3.2%
-$2.19
+77.2%
-$9.60
Total Assets $62.12M
-45.9%
$114.91M
+221.6%
$35.73M
-67.0%
$108.18M
-29.8%
$154.02M
+178.9%
$55.22M
Cash and Equivalents $59.05M
-46.7%
$110.76M
+270.7%
$29.88M
+49.9%
$19.93M
-84.0%
$124.66M
+132.5%
$53.61M
Stockholders Equity $56.18M
-45.9%
$103.83M
+202.0%
-$101.84M
-87.1%
-$54.42M
-137.0%
$147.21M
+449.5%
-$42.12M
-82.1%
R&D Expense $48.26M
+10.2%
$43.80M
+36.4%
$32.12M
-14.8%
$37.70M
+33.9%
$28.17M
+76.7%
$15.94M
Operating Income -$62.95M
-15.7%
-$54.39M
-47.3%
-$36.93M
+31.4%
-$53.85M
-35.2%
-$39.82M
-103.7%
-$19.55M
Shares Outstanding 33.42M
+35.3%
24.70M
+1.0%
24.46M
+1091.2%
2.05M

Most Recent Quarter

Metric Quarter Ending Value YoY QoQ
Net Income September 30, 2025 -$14.70M -27.2% +4.5%
Diluted EPS September 30, 2025 -$1.09 +97.0% +4.4%
Total Assets September 30, 2025 $72.83M -6.2% -15.4%
Cash and Equivalents September 30, 2025 $70.33M +15.9% -15.6%
Stockholders Equity September 30, 2025 $66.43M +149.2% -15.0%
R&D Expense September 30, 2025 $11.91M +17.8% -5.5%
Operating Income September 30, 2025 -$15.50M -34.7% +5.0%
Shares Outstanding September 30, 2024 3.34M -90.1% -90.0%
  • OnKure Therapeutics, Inc. reported Net Income of -$59.52 million for fiscal year 2025.
  • OnKure Therapeutics, Inc. showed a decrease of -13.0% in Net Income compared to the prior fiscal year.
  • OnKure Therapeutics, Inc. reported Diluted EPS of $4.40 per share (loss) for fiscal year 2025.
  • OnKure Therapeutics, Inc. showed an increase of +71.2% in Diluted EPS compared to the prior fiscal year.
  • OnKure Therapeutics, Inc. reported Total Assets of $62.12 million for fiscal year 2025.
  • OnKure Therapeutics, Inc. showed a decrease of -45.9% in Total Assets compared to the prior fiscal year.
  • OnKure Therapeutics, Inc. reported Cash and Equivalents of $59.05 million for fiscal year 2025.
  • OnKure Therapeutics, Inc. showed a decrease of -46.7% in Cash and Equivalents compared to the prior fiscal year.
  • OnKure Therapeutics, Inc. reported Stockholders Equity of $56.18 million for fiscal year 2025.
  • OnKure Therapeutics, Inc. showed a decrease of -45.9% in Stockholders Equity compared to the prior fiscal year.
  • OnKure Therapeutics, Inc. reported R&D Expense of $48.26 million for fiscal year 2025.
  • OnKure Therapeutics, Inc. showed an increase of +10.2% in R&D Expense compared to the prior fiscal year.
  • OnKure Therapeutics, Inc. reported Operating Income of -$62.95 million for fiscal year 2025.
  • OnKure Therapeutics, Inc. showed a decrease of -15.7% in Operating Income compared to the prior fiscal year.
  • OnKure Therapeutics, Inc. reported Shares Outstanding of 33.42 million shares for fiscal year 2023.
  • OnKure Therapeutics, Inc. showed an increase of +35.3% in Shares Outstanding compared to the prior fiscal year.
  • All figures are sourced from SEC EDGAR XBRL filings, last verified June 17, 2026.

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