Prelude Therapeutics Inc Financial Summary

Quick Answer

Prelude Therapeutics Inc reported Total Revenue of $12.14 million for fiscal year 2025.

Prelude Therapeutics Inc — Key Financials by Year

Metric 2025 2024 2023 2022 2021 2020
Total Revenue $12.14M
+73.4%
$7.00M
Revenue (ASC 606) $12.14M
+73.4%
$7.00M
Net Income -$99.50M
+21.8%
-$127.17M
-4.4%
-$121.83M
-5.5%
-$115.44M
-3.4%
-$111.69M
-96.2%
-$56.93M
-106.5%
Diluted EPS -$1.29
+23.2%
-$1.68
+16.8%
-$2.02
+17.2%
-$2.44
-0.4%
-$2.43
Total Assets $141.31M
-19.5%
$175.51M
-36.8%
$277.67M
+25.9%
$220.50M
-27.7%
$305.10M
+36.5%
$223.59M
+922.3%
Cash and Equivalents $35.26M
+182.6%
$12.47M
-50.7%
$25.29M
-17.4%
$30.61M
-3.8%
$31.83M
-85.4%
$218.31M
+1056.4%
Stockholders Equity $68.64M
-47.8%
$131.46M
-44.6%
$237.09M
+21.3%
$195.44M
-31.6%
$285.90M
+34.7%
$212.18M
+529.4%
R&D Expense $94.30M
-20.1%
$118.00M
+14.1%
$103.39M
+11.3%
$92.89M
+7.0%
$86.78M
+80.1%
$48.18M
+98.4%
Operating Income -$104.57M
+25.2%
-$139.71M
-5.6%
-$132.28M
-7.1%
-$123.54M
-8.6%
-$113.73M
-93.5%
-$58.76M
-109.1%

Most Recent Quarter

Metric Quarter Ending Value YoY QoQ
Total Revenue September 30, 2025 $6.50M +116.7% +116.7%
Revenue (ASC 606) September 30, 2025 $6.50M +116.7% +116.7%
Net Income September 30, 2025 -$19.73M +38.9% +36.8%
Diluted EPS September 30, 2025 -$0.26 +39.5% +36.6%
Total Assets September 30, 2025 $94.75M -52.0% -17.5%
Cash and Equivalents September 30, 2025 $47.53M +326.9% +84.6%
Stockholders Equity September 30, 2025 $58.53M -62.6% -22.8%
R&D Expense September 30, 2025 $21.71M -26.3% -15.8%
Operating Income September 30, 2025 -$20.42M +40.6% +36.6%
  • Prelude Therapeutics Inc reported Total Revenue of $12.14 million for fiscal year 2025.
  • Prelude Therapeutics Inc showed an increase of +73.4% in Total Revenue compared to the prior fiscal year.
  • Prelude Therapeutics Inc reported Revenue (ASC 606) of $12.14 million for fiscal year 2025.
  • Prelude Therapeutics Inc showed an increase of +73.4% in Revenue (ASC 606) compared to the prior fiscal year.
  • Prelude Therapeutics Inc reported Net Income of -$99.50 million for fiscal year 2025.
  • Prelude Therapeutics Inc showed an increase of +21.8% in Net Income compared to the prior fiscal year.
  • Prelude Therapeutics Inc reported Diluted EPS of $1.29 per share (loss) for fiscal year 2025.
  • Prelude Therapeutics Inc showed an increase of +23.2% in Diluted EPS compared to the prior fiscal year.
  • Prelude Therapeutics Inc reported Total Assets of $141.31 million for fiscal year 2025.
  • Prelude Therapeutics Inc showed a decrease of -19.5% in Total Assets compared to the prior fiscal year.
  • Prelude Therapeutics Inc reported Cash and Equivalents of $35.26 million for fiscal year 2025.
  • Prelude Therapeutics Inc showed an increase of +182.6% in Cash and Equivalents compared to the prior fiscal year.
  • Prelude Therapeutics Inc reported Stockholders Equity of $68.64 million for fiscal year 2025.
  • Prelude Therapeutics Inc showed a decrease of -47.8% in Stockholders Equity compared to the prior fiscal year.
  • Prelude Therapeutics Inc reported R&D Expense of $94.30 million for fiscal year 2025.
  • Prelude Therapeutics Inc showed a decrease of -20.1% in R&D Expense compared to the prior fiscal year.
  • Prelude Therapeutics Inc reported Operating Income of -$104.57 million for fiscal year 2025.
  • Prelude Therapeutics Inc showed an increase of +25.2% in Operating Income compared to the prior fiscal year.
  • All figures are sourced from SEC EDGAR XBRL filings, last verified June 17, 2026.

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