Prelude Therapeutics Inc Financial Summary

Complete Filing Data

Prelude Therapeutics Inc reported Stockholders Equity of $68.64 million for FY2025.

All values from 10-K, 20-F, and 10-Q filings on SEC EDGAR, organized by financial statement. Scroll each table horizontally for the full history. Blank cells mean Prelude Therapeutics Inc did not report that metric for that period in XBRL — often because accounting standards changed which tag a company files under (for example, most companies moved revenue to the ASC-606 tag in 2018), so a metric may continue in a different row. Rows marked * merge those successor tags into one continuous series, preferring the audited value from the newest-standard tag where periods overlap.

Income Statement

Annual (10-K / 20-F)

Metric \ Fiscal YearFY2025FY2024FY2023FY2022FY2021FY2020FY2019
Net Income *-$99.5M-$127.2M-$121.8M-$115.4M-$111.7M-$56.9M-$27.6M
Research And Development Expense$94.3M$118.0M$103.4M$92.9M$86.8M$48.2M$24.3M
Other Nonoperating Income Expense$5.1M$12.5M$10.4M$8.1M$2.0M$1.8M$539.0K
Operating Income Loss-$104.6M-$139.7M-$132.3M-$123.5M-$113.7M-$58.8M-$28.1M
Operating Expenses$116.7M$146.7M$132.3M$123.5M$113.7M$58.8M$28.1M
General And Administrative Expense$22.4M$28.7M$28.9M$30.7M$27.0M$10.6M$3.8M
Comprehensive Income Net Of Tax-$99.5M-$127.4M-$119.9M-$116.4M-$112.4M-$56.9M
Other Comprehensive Income Availableforsale Securities Adjustment Net Of Tax Portion Attributable To Parent-$27.0K-$188.0K$1.9M-$981.0K-$711.0K
Other Comprehensive Income Loss Available For Sale Securities Adjustment Net Of Tax-$27.0K-$188.0K$1.9M-$981.0K-$711.0K
Revenue From Contract With Customer Excluding Assessed Tax$12.1M$7.0M

Quarterly (10-Q, single quarters)

Metric \ QuarterQ3 2025Q2 2025Q1 2025Q3 2024Q2 2024Q1 2024Q3 2023Q2 2023Q1 2023Q3 2022Q2 2022Q1 2022Q3 2021Q2 2021Q1 2021Q3 2020Q2 2020Q1 2020Q3 2019Q2 2019Q1 2019
Net Income *-$19.7M-$31.2M-$32.1M-$32.3M-$34.7M-$31.4M-$30.6M-$30.4M-$27.7M-$30.0M-$27.4M-$29.5M-$30.7M-$26.9M-$21.3M-$16.8M-$11.4M-$9.5M-$6.7M-$5.6M-$5.2M
Research And Development Expense$21.7M$25.8M$28.8M$29.5M$29.5M$27.4M$26.3M$25.0M$21.8M$22.9M$21.3M$22.8M$22.7M$22.4M$16.5M$15.3M$9.8M$8.5M$5.5M
Other Nonoperating Income Expense$693.0K$963.0K$2.5M$2.1M$2.4M$2.9M$2.8M$2.0M$1.4M$448.0K$2.1M$823.0K$149.0K$1.1M$667.0K$1.4M$28.0K$226.0K$150.0K
Operating Income Loss-$20.4M-$32.2M-$34.6M-$34.4M-$37.2M-$34.3M-$33.4M-$32.4M-$29.1M-$30.4M-$29.5M-$30.3M-$30.8M-$27.9M-$22.0M-$18.1M-$11.4M-$9.7M-$6.9M
Operating Expenses$26.9M$32.2M$34.6M$37.4M$37.2M$34.3M$33.4M$32.4M$29.1M$30.4M$29.5M$30.3M$30.8M$27.9M$22.0M$18.1M$11.4M$9.7M$6.9M
General And Administrative Expense$5.2M$6.4M$5.8M$7.9M$7.7M$6.9M$7.1M$7.4M$7.3M$7.5M$8.2M$7.5M$8.1M$5.5M$5.5M$2.9M$1.7M$1.2M$1.4M
Comprehensive Income Net Of Tax-$19.7M-$31.2M-$32.1M-$31.8M-$34.8M-$31.9M-$30.5M-$30.7M-$26.4M-$30.0M-$27.4M-$31.1M-$30.9M-$26.9M-$21.3M-$16.8M
Other Comprehensive Income Availableforsale Securities Adjustment Net Of Tax Portion Attributable To Parent$3.0K-$13.0K-$23.0K$457.0K-$55.0K-$458.0K$106.0K-$313.0K$1.3M-$69.0K$19.0K-$1.6M-$176.0K
Other Comprehensive Income Loss Available For Sale Securities Adjustment Net Of Tax$3.0K-$13.0K-$23.0K$457.0K-$55.0K-$458.0K$106.0K-$313.0K$1.3M-$69.0K$19.0K-$1.6M
Revenue From Contract With Customer Excluding Assessed Tax$6.5M$3.0M

Balance Sheet

Annual (10-K / 20-F)

Metric \ Fiscal YearFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018
Stockholders Equity$68.6M$131.5M$237.1M$195.4M$285.9M$212.2M-$49.4M-$22.7M
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations$38.5M$16.5M$29.3M$34.6M$35.9M$218.3M$18.9M$15.6M
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect$22.0M-$12.8M-$5.3M-$1.2M-$182.4M$199.4M$3.3M
Retained Earnings Accumulated Deficit-$683.1M-$583.6M-$456.4M-$334.6M-$219.1M-$107.4M-$50.5M
Property Plant And Equipment Net$5.1M$6.8M$7.3M$4.9M$3.9M$2.5M$1.6M
Liabilities Current$53.0M$25.6M$21.8M$21.7M$19.2M$11.4M$4.8M
Liabilities And Stockholders Equity$141.3M$175.5M$277.7M$220.5M$305.1M$223.6M$21.9M
Liabilities$72.7M$44.1M$40.6M$25.1M$19.2M$11.4M$4.8M
Cash And Cash Equivalents At Carrying Value$35.3M$12.5M$25.3M$30.6M$31.8M$218.3M$18.9M
Assets Current$105.7M$135.9M$235.6M$204.4M$295.1M$220.8M$20.2M
Assets$141.3M$175.5M$277.7M$220.5M$305.1M$223.6M$21.9M
Additional Paid In Capital Common Stock$751.7M$715.0M$693.3M$531.7M$505.7M$319.6M$1.1M
Accrued Liabilities Current$12.5M$15.2M$15.8M$13.1M$9.6M$7.5M$2.6M
Accounts Payable Current$4.0M$7.7M$4.6M$6.8M$7.8M$3.9M$2.0M
Prepaid Expense And Other Assets Current$2.5M$2.3M$2.7M$2.7M$3.9M$2.5M$1.3M
Other Liabilities Noncurrent$2.8M$3.1M$3.3M$3.4M$0.00$32.0K$5.0K
Operating Lease Right Of Use Asset$27.2M$28.7M$30.4M$1.8M$1.7M
Operating Lease Liability Current$2.7M$2.5M$1.5M$1.8M$1.7M
Marketable Securities Current$68.0M$121.1M$207.6M$171.1M$259.4M
Accumulated Other Comprehensive Income Loss Net Of Tax$8.0K$35.0K$223.0K-$1.7M-$711.0K
Restricted Cash$3.2M$4.0M$4.0M$4.0M$4.0M
Operating Lease Right Of Use Asset Amortization Expense$1.5M$1.6M$1.9M$1.7M$1.3M
Accretion Amortization Of Discounts And Premiums Investments$371.0K$4.6M$3.5M-$2.6M-$1.4M
Unrealized Gain Loss On Marketable Securities-$27.0K-$188.0K$1.9M-$981.0K-$711.0K
Other Assets$5.4M$303.0K$301.0K
Operating Lease Liability Noncurrent$15.0M$15.3M$15.4M
Right Of Use Asset Obtained In Exchange For Operating Lease Liability$16.7M$1.8M$567.0K
Prepaid Expense And Other Assets Noncurrent$110.0K$110.0K$295.0K$5.4M
Repayments Of Long Term Capital Lease Obligations$258.0K$124.0K
Offering Costs In Accounts Payable$24.0K
Finance Lease Liability Current$0.00$208.0K
Offering Costs In Accrued Expenses And Other Current Liabilities$131.0K
Finance Lease Principal Payments$208.0K$395.0K
Property And Equipment In Accounts Payable And Accured Expenses And Other Currents Liabilites

Quarterly (10-Q, single quarters)

Metric \ QuarterQ3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023Q2 2023Q1 2023Q3 2022Q2 2022Q1 2022Q3 2021Q2 2021Q1 2021Q3 2020Q2 2020Q1 2020Q3 2019Q2 2019Q1 2019
Stockholders Equity$58.5M$75.8M$103.2M$156.4M$182.3M$210.7M$238.3M$262.1M$175.3M$217.4M$240.8M$261.8M$311.2M$334.4M$356.6M$228.3M-$69.3M-$58.6M-$39.7M-$33.3M-$27.9M
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations$50.8M$29.8M$44.3M$15.2M$31.9M$28.8M$19.9M$30.5M$22.2M$56.1M$54.8M$55.7M$61.4M$343.1M$363.0M$234.8M$29.7M$38.7M$27.6M
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect$27.8M-$584.0K-$12.4M$19.8M$144.7M$19.8M
Retained Earnings Accumulated Deficit-$666.6M-$646.9M-$615.6M-$554.8M-$522.6M-$487.8M-$423.3M-$392.7M-$362.3M-$305.9M-$276.0M-$248.6M-$186.3M-$155.6M-$128.7M-$88.2M
Property Plant And Equipment Net$5.5M$6.0M$6.4M$7.2M$7.6M$7.3M$6.6M$6.1M$5.4M$5.1M$4.3M$4.1M$3.2M$3.1M$2.6M$1.6M
Liabilities Current$18.2M$20.9M$19.8M$22.2M$23.3M$17.6M$16.9M$15.2M$19.7M$21.6M$15.8M$16.1M$19.7M$14.7M$12.4M$11.4M
Liabilities And Stockholders Equity$94.8M$114.9M$141.3M$197.2M$224.3M$247.1M$258.5M$280.6M$198.3M$242.3M$259.1M$280.7M$331.2M$349.6M$369.8M$239.7M
Liabilities$36.2M$39.1M$38.1M$40.8M$42.0M$36.4M$20.3M$18.6M$23.0M$24.9M$18.2M$18.9M$20.0M$15.2M$13.3M$11.4M
Cash And Cash Equivalents At Carrying Value$47.5M$25.8M$40.3M$11.1M$27.8M$24.7M$15.9M$26.4M$18.2M$52.0M$50.7M$51.6M$61.4M$343.1M$363.0M$234.8M
Assets Current$58.3M$76.9M$102.4M$156.4M$182.7M$205.4M$234.9M$260.2M$175.3M$226.9M$248.6M$270.0M$325.9M$344.6M$365.0M$238.1M
Assets$94.8M$114.9M$141.3M$197.2M$224.3M$247.1M$258.5M$280.6M$198.3M$242.3M$259.1M$280.7M$331.2M$349.6M$369.8M$239.7M
Additional Paid In Capital Common Stock$725.1M$722.7M$718.8M$711.1M$705.1M$698.8M$662.2M$655.5M$538.0M$525.7M$519.1M$512.7M$497.7M$489.9M$485.3M$316.5M
Accrued Liabilities Current$12.9M$13.2M$11.3M$13.6M$11.4M$10.1M$11.2M$8.7M$11.2M$9.9M$7.7M$6.8M$6.8M$6.4M$6.2M$6.3M
Accounts Payable Current$2.5M$5.0M$5.8M$5.9M$6.2M$5.3M$5.2M$5.6M$7.1M$10.3M$6.3M$7.4M$11.1M$6.8M$4.8M$5.1M
Prepaid Expense And Other Assets Current$3.4M$3.7M$3.3M$2.8M$2.9M$3.4M$4.4M$5.2M$3.0M$2.9M$2.3M$3.8M$5.0M$1.5M$2.0M$3.3M
Other Liabilities Noncurrent$2.9M$3.0M$3.0M$3.2M$3.2M$3.3M$3.4M$3.4M$3.4M$3.4M$2.4M$2.4M$15.0K
Operating Lease Right Of Use Asset$27.5M$27.9M$28.3M$29.2M$29.6M$30.1M$464.0K$918.0K$1.4M$1.4M$1.8M$2.2M$2.1M$1.9M$2.2M
Operating Lease Liability Current$2.7M$2.7M$2.6M$2.4M$2.2M$2.2M$475.0K$938.0K$1.4M$1.4M$1.8M$1.9M$1.8M$1.4M$1.4M
Marketable Securities Current$7.4M$47.5M$58.8M$142.5M$152.0M$177.2M$214.6M$228.5M$154.1M$172.0M$195.6M$214.6M$259.4M
Accumulated Other Comprehensive Income Loss Net Of Tax$2.0K-$1.0K$12.0K$167.0K-$290.0K-$235.0K-$605.0K-$711.0K-$398.0K-$2.4M-$2.3M-$2.3M-$176.0K
Restricted Cash$3.2M$4.0M$4.0M$4.0M$4.0M$4.0M$4.0M$4.0M$4.0M$4.0M$4.0M$4.0M
Operating Lease Right Of Use Asset Amortization Expense$384.0K$414.0K$432.0K$411.0K$282.0K
Accretion Amortization Of Discounts And Premiums Investments-$79.0K$1.5M$446.0K-$748.0K
Unrealized Gain Loss On Marketable Securities-$23.0K-$458.0K$1.3M-$1.6M
Other Assets$110.0K$110.0K$110.0K$110.0K$405.0K$405.0K$295.0K$295.0K$4.9M$309.0K$309.0K
Operating Lease Liability Noncurrent$15.1M$15.2M$15.3M$15.4M$15.5M$15.5M$390.0K$312.0K$543.0K$840.0K
Right Of Use Asset Obtained In Exchange For Operating Lease Liability$109.0K$928.0K
Prepaid Expense And Other Assets Noncurrent$12.5M$9.4M$12.3M
Repayments Of Long Term Capital Lease Obligations$95.0K
Offering Costs In Accounts Payable
Finance Lease Liability Current$0.00$0.00$53.0K$359.0K$507.0K
Offering Costs In Accrued Expenses And Other Current Liabilities
Finance Lease Principal Payments$155.0K
Property And Equipment In Accounts Payable And Accured Expenses And Other Currents Liabilites$19.0K$269.0K$21.0K

Cash Flow Statement

Annual (10-K / 20-F)

Metric \ Fiscal YearFY2025FY2024FY2023FY2022FY2021FY2020FY2019
Stock Issued During Period Value Share Based Compensation$11.9M$21.3M$25.6M$25.1M$20.9M$5.6M$846.0K
Share Based Compensation$11.9M$21.3M$25.6M$25.1M$20.9M$5.6M$846.0K
Payments To Acquire Property Plant And Equipment$67.0K$764.0K$3.5M$3.0M$2.3M$621.0K$780.0K
Net Cash Provided By Used In Operating Activities-$56.3M-$102.9M-$107.1M-$83.7M-$83.5M-$46.2M-$25.7M
Net Cash Provided By Used In Investing Activities$53.5M$90.2M-$34.6M$81.7M-$263.8M-$621.0K-$780.0K
Net Cash Provided By Used In Financing Activities$24.8M-$120.0K$136.4M$815.0K$164.9M$246.2M$29.7M
Increase Decrease In Prepaid Deferred Expense And Other Assets$197.0K-$373.0K$297.0K$3.8M$1.4M$1.2M$1.3M
Increase Decrease In Accrued Liabilities And Other Operating Liabilities-$3.0M-$808.0K$2.5M$6.8M$2.5M$4.6M$1.5M
Increase Decrease In Accounts Payable-$3.9M$3.3M-$2.3M-$347.0K$3.9M$1.2M$546.0K
Depreciation Depletion And Amortization$1.7M$1.8M$1.2M$1.3M$915.0K$542.0K$382.0K
Proceeds From Stock Options Exercised$16.0K$60.0K$47.0K$389.0K$3.5M$100.0K$5.0K
Increase Decrease In Operating Lease Liabilities$28.0K-$1.1M$1.6M$1.7M$1.4M
Payments To Acquire Marketable Securities$100.9M$52.7M$221.6M$119.2M$261.5M
Proceeds From Sale And Maturity Of Marketable Securities$154.4M$143.6M$190.5M$203.9M
Shares Paid For Tax Withholding For Share Based Compensation13.9K15.5K4.0K
Proceeds From Stock Plans$150.0K$379.0K$634.0K$426.0K$272.0K
Payments Of Stock Issuance Costs$0.00$110.0K$2.8M$303.0K$12.0K
Payments Related To Tax Withholding For Share Based Compensation$17.0K$54.0K$17.0K
Payments Of Offering Costs$739.0K$2.5M
Increase Decrease In Long Term Prepaid Expense And Other Long Term Assets$0.00-$295.0K$8.8M
Proceeds From Issuance Of Common Stock$161.4M
Proceeds From Issuance Of Common Stock And Pre Funded Warrants Net Of Issuance Costs$135.7M

Quarterly (10-Q, single quarters)

Metric \ QuarterQ3 2025Q2 2025Q1 2025Q3 2024Q2 2024Q1 2024Q3 2023Q2 2023Q1 2023Q3 2022Q2 2022Q1 2022Q3 2021Q2 2021Q1 2021Q3 2020Q2 2020Q1 2020Q3 2019Q2 2019Q1 2019
Stock Issued During Period Value Share Based Compensation$2.4M$3.8M$3.8M$5.9M$6.1M$5.5M$6.7M$6.7M$6.3M$6.4M$6.0M$6.8M$7.0M$4.2M$3.9M$1.5M$627.0K$362.0K$297.0K$141.0K$82.0K
Share Based Compensation$3.8M$5.5M$6.3M$6.8M$3.9M$362.0K
Payments To Acquire Property Plant And Equipment$47.0K$289.0K$810.0K$952.0K$986.0K$80.0K
Net Cash Provided By Used In Operating Activities-$34.2M-$31.8M-$30.1M-$21.9M-$16.1M-$9.9M
Net Cash Provided By Used In Investing Activities$62.2M$31.2M$18.0M$153.0K-$986.0K-$80.0K
Net Cash Provided By Used In Financing Activities-$160.0K-$14.0K-$269.0K$41.5M$161.8M$29.8M
Increase Decrease In Prepaid Deferred Expense And Other Assets$1.0M$788.0K$355.0K-$93.0K-$761.0K-$436.0K
Increase Decrease In Accrued Liabilities And Other Operating Liabilities-$4.0M-$5.7M-$1.9M-$401.0K-$1.4M-$1.3M
Increase Decrease In Accounts Payable-$1.9M$631.0K$374.0K$2.0K$1.6M-$72.0K
Depreciation Depletion And Amortization$435.0K$426.0K$278.0K$307.0K$160.0K$132.0K
Proceeds From Stock Options Exercised$2.0K$28.0K$153.0K$386.0K
Increase Decrease In Operating Lease Liabilities-$50.0K-$643.0K$442.0K$419.0K$161.0K
Payments To Acquire Marketable Securities$9.5M$5.5M$7.2M
Proceeds From Sale And Maturity Of Marketable Securities$71.7M$37.0M$26.0M$42.5M
Shares Paid For Tax Withholding For Share Based Compensation3.4K3.4K3.9K3.7K3.7K4.3K3.6K
Proceeds From Stock Plans
Payments Of Stock Issuance Costs$2.6M$297.0K
Payments Related To Tax Withholding For Share Based Compensation$5.0K$16.0K
Payments Of Offering Costs$739.0K$2.5M
Increase Decrease In Long Term Prepaid Expense And Other Long Term Assets$6.6M
Proceeds From Issuance Of Common Stock$161.4M
Proceeds From Issuance Of Common Stock And Pre Funded Warrants Net Of Issuance Costs

Per-Share & Share Counts

Annual (10-K / 20-F)

Metric \ Fiscal YearFY2025FY2024FY2023FY2022FY2021FY2020FY2019
Diluted EPS *-$1.29-$1.68-$2.02-$2.44-$2.43-$4.56-$16.52
Weighted Average Number Of Shares Outstanding Basic77.0M75.8M60.4M47.4M46.0M
Weighted Average Number Of Diluted Shares Outstanding77.0M75.8M60.4M47.4M46.0M
Earnings Per Share Basic$-1.29$-1.68$-2.02$-2.44$-2.43
Weighted Average Number Of Share Outstanding Basic And Diluted46.0M12.5M1.7M
Temporary Equity Par Or Stated Value Per Share$0.00$0.00

Quarterly (10-Q, single quarters)

Metric \ QuarterQ3 2025Q2 2025Q1 2025Q3 2024Q2 2024Q1 2024Q3 2023Q2 2023Q1 2023Q3 2022Q2 2022Q1 2022Q3 2021Q2 2021Q1 2021Q3 2020Q2 2020Q1 2020Q3 2019
Diluted EPS *-$0.26-$0.41-$0.42-$0.43-$0.46-$0.42-$0.45-$0.54-$0.58-$0.63-$0.58-$0.63-$0.66-$0.58-$0.47-$5.25-$5.50-$5.12-$3.93
Weighted Average Number Of Shares Outstanding Basic76.1M76.0M76.0M75.9M75.8M75.7M67.6M56.2M47.7M47.4M47.3M47.1M46.3M46.1M
Weighted Average Number Of Diluted Shares Outstanding76.1M76.0M76.0M75.9M75.8M75.7M67.6M56.2M47.7M47.4M47.3M47.1M46.3M46.1M
Earnings Per Share Basic$-0.26$-0.41$-0.42$-0.43$-0.46$-0.42$-0.45$-0.54$-0.58$-0.63$-0.58$-0.63$-0.66$-0.58
Weighted Average Number Of Share Outstanding Basic And Diluted47.1M46.3M46.1M45.1M3.2M2.1M1.9M1.7M
Temporary Equity Par Or Stated Value Per Share$0.00

Other Metrics

Annual (10-K / 20-F)

Metric \ Fiscal YearFY2025FY2024FY2023FY2022FY2021FY2020FY2019
Stock Issued During Period Value Stock Options Exercised$3.5M$100.0K$5.0K
Capital Expenditures Incurred But Not Yet Paid$0.00$10.0K$163.0K$90.0K$806.0K$765.0K$66.0K
Stock Issued During Period Value Stock Options Exercised And Vesting Of Restricted Stock Units-$1.0K$6.0K$30.0K$389.0K
Stock Issued During Period Value Employee Stock Purchase Plan$150.0K$379.0K$634.0K$426.0K$272.0K
Stock Issued During Period Value New Issues$24.6M$135.3M$161.4M$166.6M
Stock Issued During Period Shares Stock Options Exercised217.9K996.0K100.5K19.7K

Quarterly (10-Q, single quarters)

Metric \ QuarterQ3 2025Q2 2025Q3 2024Q2 2024Q1 2024Q3 2023Q2 2023Q1 2023Q3 2022Q2 2022Q1 2022Q3 2021Q2 2021Q1 2021Q3 2020Q2 2020Q1 2020Q2 2019
Stock Issued During Period Value Stock Options Exercised$148.0K$59.0K$153.0K$711.0K$422.0K$386.0K$65.0K$31.0K$5.0K
Capital Expenditures Incurred But Not Yet Paid$21.0K$354.0K$86.0K$33.0K
Stock Issued During Period Value Stock Options Exercised And Vesting Of Restricted Stock Units-$5.0K-$2.0K$43.0K-$16.0K-$14.0K-$16.0K$3.0K$28.0K
Stock Issued During Period Value Employee Stock Purchase Plan$92.0K$255.0K$348.0K$300.0K
Stock Issued During Period Value New Issues$110.4M$161.4M$166.6M
Stock Issued During Period Shares Stock Options Exercised16.0K93.0K210.3K

Most recent annual filing with the SEC: March 10, 2026

Data sourced from SEC EDGAR public filings as of August 6, 2026.