Septerna, Inc. Financial Summary

Complete Filing Data

Septerna, Inc. reported Stockholders Equity of $381.93 million for FY2025.

All values from 10-K, 20-F, and 10-Q filings on SEC EDGAR, organized by financial statement. Scroll each table horizontally for the full history. Blank cells mean Septerna, Inc. did not report that metric for that period in XBRL — often because accounting standards changed which tag a company files under (for example, most companies moved revenue to the ASC-606 tag in 2018), so a metric may continue in a different row. Rows marked * merge those successor tags into one continuous series, preferring the audited value from the newest-standard tag where periods overlap.

Income Statement

Annual (10-K / 20-F)

Metric \ Fiscal YearFY2025FY2024FY2023
Net Income *-$48.9M-$71.8M$4.2M
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest-$48.9M-$72.3M-$48.9M
Revenue From Contract With Customer Excluding Assessed Tax$46.0M$1.1M$151.0K
Research And Development Expense$97.6M$65.3M$36.0M
Other Nonoperating Income Expense-$100.0K-$90.0K$10.0K
Operating Income Loss-$68.3M-$80.8M$2.1M
Operating Expenses$114.2M$81.9M-$1.9M
Nonoperating Income Expense$19.4M$8.5M$2.8M
General And Administrative Expense$29.2M$16.6M$9.7M
Comprehensive Income Net Of Tax-$48.3M-$71.7M$4.2M
Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent$561.0K$56.0K$0.00
Other Comprehensive Income Loss Available For Sale Securities Adjustment Net Of Tax$561.0K$56.0K$0.00
Income Tax Expense Benefit$12.0K-$498.0K$691.0K

Quarterly (10-Q, single quarters)

Metric \ QuarterQ3 2025Q2 2025Q1 2025Q3 2024Q2 2024Q1 2024Q3 2023Q2 2023Q1 2023
Net Income *$8.2M-$24.8M-$21.5M-$20.5M-$16.5M-$14.1M-$10.9M-$10.6M-$9.2M
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest$8.2M-$24.8M-$21.5M-$20.7M-$16.6M-$14.3M-$10.9M
Revenue From Contract With Customer Excluding Assessed Tax$21.5M$119.0K$219.0K$176.0K$370.0K$317.0K$33.0K
Research And Development Expense$24.3M$22.2M$19.3M$17.8M$15.0M$13.2M$9.3M
Other Nonoperating Income Expense-$6.0K-$25.0K-$28.0K-$9.0K-$15.0K-$48.0K-$1.0K
Operating Income Loss$2.6M-$29.0M-$25.9M-$22.6M-$18.1M-$15.5M-$12.0M
Operating Expenses$18.9M$29.1M$26.1M$22.7M$18.4M$15.8M$12.1M
Nonoperating Income Expense$5.6M$4.1M$4.4M$1.9M$1.5M$1.2M$1.1M
General And Administrative Expense$7.1M$6.9M$6.9M$4.9M$3.4M$2.7M$2.8M
Comprehensive Income Net Of Tax$8.4M-$24.9M-$21.3M-$20.3M-$16.4M-$14.2M-$10.9M
Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent$199.0K-$22.0K$142.0K$184.0K-$1.0K-$7.0K
Other Comprehensive Income Loss Available For Sale Securities Adjustment Net Of Tax$199.0K-$22.0K$142.0K$184.0K-$1.0K-$7.0K
Income Tax Expense Benefit$0.00$0.00$0.00-$136.0K$109.0K$93.0K

Balance Sheet

Annual (10-K / 20-F)

Metric \ Fiscal YearFY2025FY2024FY2023FY2022
Stockholders Equity$381.9M$420.0M-$38.4M-$44.2M
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations$121.6M$239.1M$89.4M$31.5M
Cash And Cash Equivalents At Carrying Value$120.7M$238.2M$88.5M
Retained Earnings Accumulated Deficit-$167.3M-$118.4M-$46.6M
Restricted Cash Noncurrent$905.0K$905.0K$905.0K
Restricted Cash$905.0K$905.0K$905.0K
Property Plant And Equipment Net$4.4M$5.1M$4.7M
Prepaid Expense And Other Assets Current$9.5M$5.7M$1.4M
Other Liabilities Noncurrent$0.00$33.0K$546.0K
Other Assets Noncurrent$816.0K$267.0K$97.0K
Operating Lease Right Of Use Asset$21.5M$23.6M$12.5M
Operating Lease Liability Noncurrent$21.4M$23.6M$12.6M
Operating Lease Expense$2.1M$1.4M$807.0K
Liabilities Current$86.9M$12.8M$6.9M
Liabilities And Stockholders Equity$596.2M$456.6M$130.9M
Liabilities$214.3M$36.5M$20.0M
Common Stock Value$45.0K$44.0K$3.0K
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect-$117.5M$149.7M$57.9M
Assets Current$411.0M$356.8M$112.7M
Assets$596.2M$456.6M$130.9M
Additional Paid In Capital Common Stock$548.5M$538.3M$8.2M
Accrued Liabilities Current$12.2M$7.8M$4.3M
Accounts Receivable Net Current$10.4M$171.0K$151.0K
Accounts Payable Current$10.3M$3.2M$2.6M
Operating Lease Liability Current$2.2M$1.9M$0.00
Marketable Securities Noncurrent$157.6M$69.9M$0.00
Marketable Securities Current$270.4M$112.7M$0.00
Accumulated Other Comprehensive Income Loss Net Of Tax$617.0K$56.0K$0.00
Repurchases Of Unvested Restricted Common Stock$1.0K$1.0K$1.0K
Marketable Securities Unrealized Gain Loss
Accretion Amortization Of Discounts And Premiums Investments$3.4M$1.4M$0.00

Quarterly (10-Q, single quarters)

Metric \ QuarterQ3 2025Q2 2025Q1 2025Q3 2024Q2 2024Q1 2024Q3 2023Q2 2023Q1 2023
Stockholders Equity$388.7M$377.6M$400.3M-$87.4M-$67.8M-$51.9M-$73.8M-$63.3M-$53.0M
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations$320.9M$190.2M$211.0M$89.1M$132.1M$82.2M$99.4M
Cash And Cash Equivalents At Carrying Value$320.0M$189.3M$210.0M$88.2M$131.2M$81.3M$98.5M
Retained Earnings Accumulated Deficit-$156.5M-$164.7M-$139.9M-$97.7M
Restricted Cash Noncurrent$905.0K$905.0K$905.0K$905.0K
Restricted Cash$905.0K$905.0K$905.0K$905.0K$905.0K$905.0K$905.0K
Property Plant And Equipment Net$4.3M$4.7M$5.0M$5.4M
Prepaid Expense And Other Assets Current$8.7M$7.4M$6.2M$2.7M
Other Liabilities Noncurrent$0.00$2.0K$27.0K$191.0K
Other Assets Noncurrent$501.0K$300.0K$277.0K$3.5M
Operating Lease Right Of Use Asset$22.0M$22.6M$23.1M$24.1M
Operating Lease Liability Noncurrent$22.0M$22.5M$23.1M$24.1M
Operating Lease Expense$516.0K$243.0K
Liabilities Current$75.3M$15.1M$10.6M$13.2M
Liabilities And Stockholders Equity$606.7M$415.2M$434.0M$174.3M
Liabilities$217.9M$37.7M$33.8M$37.5M
Common Stock Value$45.0K$45.0K$44.0K$3.0K
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect-$28.2M-$7.1M
Assets Current$491.7M$334.1M$342.5M$133.4M
Assets$606.7M$415.2M$434.0M$174.3M
Additional Paid In Capital Common Stock$544.8M$542.0M$539.9M$10.1M
Accrued Liabilities Current$7.8M$6.6M$4.4M$6.0M
Accounts Receivable Net Current$8.6M$151.0K$250.0K$210.0K
Accounts Payable Current$3.7M$6.5M$4.3M$6.1M
Operating Lease Liability Current$2.1M$2.0M$1.9M$1.1M
Marketable Securities Noncurrent$87.2M$52.6M$62.2M$7.0M
Marketable Securities Current$154.4M$137.3M$126.0M$42.3M
Accumulated Other Comprehensive Income Loss Net Of Tax$375.0K$176.0K$198.0K$176.0K
Repurchases Of Unvested Restricted Common Stock$1.0K
Marketable Securities Unrealized Gain Loss$199.0K-$22.0K$142.0K$184.0K-$1.0K-$7.0K
Accretion Amortization Of Discounts And Premiums Investments$965.0K$72.0K

Cash Flow Statement

Annual (10-K / 20-F)

Metric \ Fiscal YearFY2025FY2024FY2023
Share Based Compensation$8.5M$3.2M$1.6M
Payments To Acquire Property Plant And Equipment$518.0K$2.1M$2.9M
Net Cash Provided By Used In Operating Activities$110.2M-$67.5M-$38.7M
Net Cash Provided By Used In Investing Activities-$229.4M-$160.6M$22.1M
Increase Decrease In Prepaid Deferred Expense And Other Assets$3.8M$4.3M$136.0K
Increase Decrease In Other Operating Assets$554.0K$170.0K-$165.0K
Increase Decrease In Operating Lease Liability-$1.9M$448.0K-$770.0K
Increase Decrease In Accrued Liabilities And Other Operating Liabilities$4.4M$3.6M$2.5M
Increase Decrease In Accounts Receivable$10.2M$20.0K$151.0K
Increase Decrease In Accounts Payable$6.6M$723.0K-$653.0K
Proceeds From Stock Options Exercised$973.0K$52.0K$0.00
Net Cash Provided By Used In Financing Activities$1.7M$377.8M$74.5M
Proceeds From Sale Of Non Financial Asset$12.5M$22.6M$25.0M
Proceeds From Sale And Maturity Of Marketable Securities$32.3M$0.00
Proceeds From Issuance Of Convertible Preferred Stock$0.00$74.9M$74.5M
Payments To Acquire Marketable Securities$213.4M$0.00

Quarterly (10-Q, single quarters)

Metric \ QuarterQ3 2025Q2 2025Q1 2025Q3 2024Q2 2024Q1 2024
Share Based Compensation$2.5M$1.8M$1.5M$683.0K$628.0K$577.0K
Payments To Acquire Property Plant And Equipment$382.0K$764.0K
Net Cash Provided By Used In Operating Activities-$23.3M-$16.7M
Net Cash Provided By Used In Investing Activities-$4.9M$9.6M
Increase Decrease In Prepaid Deferred Expense And Other Assets$488.0K$1.4M
Increase Decrease In Other Operating Assets$9.0K$24.0K
Increase Decrease In Operating Lease Liability-$450.0K-$144.0K
Increase Decrease In Accrued Liabilities And Other Operating Liabilities-$3.4M-$1.6M
Increase Decrease In Accounts Receivable$79.0K$240.0K
Increase Decrease In Accounts Payable$1.2M-$143.0K
Proceeds From Stock Options Exercised$66.0K$1.0K
Net Cash Provided By Used In Financing Activities$66.0K
Proceeds From Sale Of Non Financial Asset$22.6M
Proceeds From Sale And Maturity Of Marketable Securities$45.2M$0.00
Proceeds From Issuance Of Convertible Preferred Stock
Payments To Acquire Marketable Securities$49.7M$12.3M

Per-Share & Share Counts

Annual (10-K / 20-F)

Metric \ Fiscal YearFY2025FY2024FY2023
Weighted Average Number Of Shares Outstanding Basic44.3M9.9M1.9M
Weighted Average Number Of Diluted Shares Outstanding44.3M9.9M2.2M
Earnings Per Share Diluted$-1.10$-7.26$0.29
Earnings Per Share Basic$-1.10$-7.26$0.29
Preferred Stock Shares Outstanding0.000.000.00
Preferred Stock Shares Issued0.000.000.00
Preferred Stock Shares Authorized10.0M10.0M0.00
Common Stock Shares Outstanding44.8M44.4M3.2M
Common Stock Shares Issued44.8M44.4M3.2M
Common Stock Shares Authorized500.0M500.0M260.6M
Common Stock Par Or Stated Value Per Share$0.00$0.00$0.00
Preferred Stock Par Or Stated Value Per Share$0.00$0.00

Quarterly (10-Q, single quarters)

Metric \ QuarterQ3 2025Q2 2025Q1 2025Q3 2024Q2 2024Q1 2024Q3 2023
Weighted Average Number Of Shares Outstanding Basic44.3M44.2M43.9M2.4M2.3M2.2M2.0M
Weighted Average Number Of Diluted Shares Outstanding45.6M44.2M43.9M2.4M2.3M2.2M2.0M
Earnings Per Share Diluted$0.18$-0.56$-0.49$-8.40$-7.03$-6.35$-5.45
Earnings Per Share Basic$0.18$-0.56$-0.49$-8.40$-7.03$-6.35$-5.45
Preferred Stock Shares Outstanding0.000.000.00
Preferred Stock Shares Issued0.000.000.00
Preferred Stock Shares Authorized10.0M10.0M10.0M
Common Stock Shares Outstanding44.6M44.6M44.4M
Common Stock Shares Issued44.6M44.6M44.4M
Common Stock Shares Authorized500.0M500.0M500.0M
Common Stock Par Or Stated Value Per Share$0.00$0.00$0.00
Preferred Stock Par Or Stated Value Per Share$0.00$0.00$0.00

Other Metrics

Annual (10-K / 20-F)

Metric \ Fiscal YearFY2025FY2024FY2023
Stock Issued During Period Values Restricted Stock Award Vested$23.0K$21.0K$27.0K
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value$8.5M$3.2M$1.6M
Stock Issued During Period Value Stock Options Exercised$982.0K$66.0K
Investment Income Interest$19.5M$8.6M$2.8M
Other Noncash Income Expense-$56.0K-$45.0K-$30.0K
Depreciation And Amortization$1.6M$1.4M$848.0K
Restricted Stock Options Subject To Repurchase$131.2K$576.8K$1.0M

Quarterly (10-Q, single quarters)

Metric \ QuarterQ3 2025Q2 2025Q1 2025Q3 2024Q2 2024Q1 2024Q3 2023Q2 2023Q1 2023
Stock Issued During Period Values Restricted Stock Award Vested$6.0K$6.0K$5.0K$6.0K$4.0K$6.0K$6.0K$9.0K$6.0K
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value$2.5M$1.8M$1.5M$683.0K$628.0K$577.0K$347.0K$355.0K$343.0K
Stock Issued During Period Value Stock Options Exercised$264.0K$339.0K$66.0K$5.0K$10.0K$1.0K
Investment Income Interest$5.6M$4.2M$4.5M$1.9M$1.5M$1.3M$1.1M
Other Noncash Income Expense$11.0K-$13.0K
Depreciation And Amortization$397.0K$316.0K
Restricted Stock Options Subject To Repurchase$228.0K$341.7K$457.1K

Most recent annual filing with the SEC: March 9, 2026

Data sourced from SEC EDGAR public filings as of August 5, 2026.