Septerna, Inc. Financial Summary

Quick Answer

Septerna, Inc. reported Total Revenue of $45.95 million for fiscal year 2025.

Septerna, Inc. — Key Financials by Year

Metric 2025 2024 2023 2022
Total Revenue $45.95M
+4174.5%
$1.07M
+611.9%
$151.0K
Revenue (ASC 606) $45.95M
+4174.5%
$1.07M
+611.9%
$151.0K
Net Income -$48.88M
+31.9%
-$71.80M
-1817.7%
$4.18M
Diluted EPS -$1.10
+84.8%
-$7.26
-2603.4%
$0.29
Total Assets $596.19M
+30.6%
$456.55M
+248.9%
$130.87M
Cash and Equivalents $120.72M
-49.3%
$238.20M
+169.2%
$88.48M
Stockholders Equity $381.93M
-9.1%
$420.05M
+1194.6%
-$38.37M
+13.2%
-$44.20M
R&D Expense $97.58M
+49.4%
$65.34M
+81.6%
$35.98M
Operating Income -$68.30M
+15.5%
-$80.82M
-3995.1%
$2.08M
Shares Outstanding 44.81M
+0.9%
44.42M
+1302.2%
3.17M

Most Recent Quarter

Metric Quarter Ending Value YoY QoQ
Total Revenue September 30, 2025 $21.50M +12113.1% +17963.0%
Revenue (ASC 606) September 30, 2025 $21.50M +12113.1% +17963.0%
Net Income September 30, 2025 $8.17M +139.8% +132.9%
Diluted EPS September 30, 2025 $0.18 +102.1% +132.1%
Total Assets September 30, 2025 $606.65M +248.1% +46.1%
Cash and Equivalents September 30, 2025 $319.99M +262.6% +69.0%
Stockholders Equity September 30, 2025 $388.73M +544.7% +3.0%
R&D Expense September 30, 2025 $24.26M +36.1% +9.4%
Operating Income September 30, 2025 $2.61M +111.6% +109.0%
Shares Outstanding September 30, 2025 44.64M +0.2%
  • Septerna, Inc. reported Total Revenue of $45.95 million for fiscal year 2025.
  • Septerna, Inc. showed an increase of +4174.5% in Total Revenue compared to the prior fiscal year.
  • Septerna, Inc. reported Revenue (ASC 606) of $45.95 million for fiscal year 2025.
  • Septerna, Inc. showed an increase of +4174.5% in Revenue (ASC 606) compared to the prior fiscal year.
  • Septerna, Inc. reported Net Income of -$48.88 million for fiscal year 2025.
  • Septerna, Inc. showed an increase of +31.9% in Net Income compared to the prior fiscal year.
  • Septerna, Inc. reported Diluted EPS of $1.10 per share (loss) for fiscal year 2025.
  • Septerna, Inc. showed an increase of +84.8% in Diluted EPS compared to the prior fiscal year.
  • Septerna, Inc. reported Total Assets of $596.19 million for fiscal year 2025.
  • Septerna, Inc. showed an increase of +30.6% in Total Assets compared to the prior fiscal year.
  • Septerna, Inc. reported Cash and Equivalents of $120.72 million for fiscal year 2025.
  • Septerna, Inc. showed a decrease of -49.3% in Cash and Equivalents compared to the prior fiscal year.
  • Septerna, Inc. reported Stockholders Equity of $381.93 million for fiscal year 2025.
  • Septerna, Inc. showed a decrease of -9.1% in Stockholders Equity compared to the prior fiscal year.
  • Septerna, Inc. reported R&D Expense of $97.58 million for fiscal year 2025.
  • Septerna, Inc. showed an increase of +49.4% in R&D Expense compared to the prior fiscal year.
  • Septerna, Inc. reported Operating Income of -$68.30 million for fiscal year 2025.
  • Septerna, Inc. showed an increase of +15.5% in Operating Income compared to the prior fiscal year.
  • Septerna, Inc. reported Shares Outstanding of 44.81 million shares for fiscal year 2025.
  • Septerna, Inc. showed an increase of +0.9% in Shares Outstanding compared to the prior fiscal year.
  • All figures are sourced from SEC EDGAR XBRL filings, last verified June 17, 2026.

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