Silence Therapeutics plc Financial Summary

Quick Answer

Silence Therapeutics plc reported Total Revenue of $559.0 thousand for fiscal year 2025.

Silence Therapeutics plc — Key Financials by Year

Metric 2025 2024 2023 2022 2021 2020
Total Revenue $559.0K
-98.7%
$43.26M
+36.7%
$31.64M
+46.1%
$21.66M
Revenue (ASC 606) $559.0K
-98.7%
$43.26M
+36.7%
$31.64M
+46.1%
$21.66M
Net Income -$88.61M
-95.6%
-$45.31M
+16.4%
-$54.23M
-7.7%
-$50.33M
Diluted EPS -$0.63
-90.9%
-$0.33
+32.7%
-$0.49
+5.8%
-$0.52
Total Assets $131.44M
-35.1%
$202.63M
+69.6%
$119.45M
Cash and Equivalents $11.28M
-90.7%
$121.33M
+76.4%
$68.79M
Stockholders Equity $62.30M
-53.5%
$134.02M
+509.4%
$21.99M
-19.2%
$27.22M
+120.0%
$12.37M
R&D Expense $67.75M
-0.2%
$67.88M
+19.2%
$56.94M
+30.7%
$43.55M
+41.6%
$30.77M
+52.2%
$20.21M
+51.5%
Operating Income -$91.08M
-43.8%
-$63.32M
+1.7%
-$64.38M
-5.5%
-$61.04M
Gross Profit $344.0K
-98.9%
$31.45M
+67.5%
$18.78M
+129.2%
$8.19M
+65.2%
$4.96M
+188.8%
$1.72M
+603.7%

Most Recent Quarter

Metric Quarter Ending Value YoY QoQ
Total Revenue September 30, 2025 $159.0K -89.4% -29.0%
Revenue (ASC 606) September 30, 2025 $159.0K -89.4% -29.0%
Net Income September 30, 2025 -$20.96M +41.0% +23.4%
Diluted EPS September 30, 2025 -$0.15 +40.0% +21.1%
Total Assets September 30, 2025 $146.79M -11.2%
Cash and Equivalents September 30, 2025 $82.03M +96.5%
Stockholders Equity September 30, 2025 $74.06M -41.5% -21.3%
R&D Expense September 30, 2025 $20.54M +1.9% +16.4%
Operating Income September 30, 2025 -$26.24M +12.5% -9.5%
Gross Profit September 30, 2025 $95.0K +104.4% -31.7%
  • Silence Therapeutics plc reported Total Revenue of $559.0 thousand for fiscal year 2025.
  • Silence Therapeutics plc showed a decrease of -98.7% in Total Revenue compared to the prior fiscal year.
  • Silence Therapeutics plc reported Revenue (ASC 606) of $559.0 thousand for fiscal year 2025.
  • Silence Therapeutics plc showed a decrease of -98.7% in Revenue (ASC 606) compared to the prior fiscal year.
  • Silence Therapeutics plc reported Net Income of -$88.61 million for fiscal year 2025.
  • Silence Therapeutics plc showed a decrease of -95.6% in Net Income compared to the prior fiscal year.
  • Silence Therapeutics plc reported Diluted EPS of $0.63 per share (loss) for fiscal year 2025.
  • Silence Therapeutics plc showed a decrease of -90.9% in Diluted EPS compared to the prior fiscal year.
  • Silence Therapeutics plc reported Total Assets of $131.44 million for fiscal year 2025.
  • Silence Therapeutics plc showed a decrease of -35.1% in Total Assets compared to the prior fiscal year.
  • Silence Therapeutics plc reported Cash and Equivalents of $11.28 million for fiscal year 2025.
  • Silence Therapeutics plc showed a decrease of -90.7% in Cash and Equivalents compared to the prior fiscal year.
  • Silence Therapeutics plc reported Stockholders Equity of $62.30 million for fiscal year 2025.
  • Silence Therapeutics plc showed a decrease of -53.5% in Stockholders Equity compared to the prior fiscal year.
  • Silence Therapeutics plc reported R&D Expense of $67.75 million for fiscal year 2025.
  • Silence Therapeutics plc showed a decrease of -0.2% in R&D Expense compared to the prior fiscal year.
  • Silence Therapeutics plc reported Operating Income of -$91.08 million for fiscal year 2025.
  • Silence Therapeutics plc showed a decrease of -43.8% in Operating Income compared to the prior fiscal year.
  • Silence Therapeutics plc reported Gross Profit of $344.0 thousand for fiscal year 2025.
  • Silence Therapeutics plc showed a decrease of -98.9% in Gross Profit compared to the prior fiscal year.
  • All figures are sourced from SEC EDGAR XBRL filings, last verified June 17, 2026.

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