Denali Therapeutics Inc. Net Income

Quick Answer

Denali Therapeutics Inc. reported Net Income of -$512.54 million for fiscal year 2025.

Denali Therapeutics Inc. Net Income — Annual History

Fiscal Year Net Income YoY Change
2025 -$512.54M -21.2%
2024 -$422.77M -191.1%
2023 -$145.22M +55.5%
2022 -$325.99M -12.2%
2021 -$290.58M -508.5%
2020 $71.14M +136.0%
2019 -$197.61M -445.3%
2018 -$36.24M +58.9%
2017 -$88.19M -1.8%
2016 -$86.65M

Quarterly Net Income

Quarter Ending Net Income YoY QoQ
September 30, 2025 -$126.90M -18.4% -2.2%
June 30, 2025 -$124.12M -25.3% +6.7%
March 31, 2025 -$132.97M -30.6% -24.0%
September 30, 2024 -$107.19M -7.9% -8.2%
June 30, 2024 -$99.03M -154.0% +2.7%
March 31, 2024 -$101.80M +7.3% -2.5%
September 30, 2023 -$99.35M +3.8% -154.2%
June 30, 2023 $183.38M +411.9% +267.0%
  • Denali Therapeutics Inc. showed a decrease of -21.2% in Net Income compared to the prior fiscal year.
  • Over the 2016–2025 period, Denali Therapeutics Inc.’s net income has declined by 491.5% (from -$86.65 million to -$512.54 million).
  • The most recent figure is from Denali Therapeutics Inc.’s fiscal year 2025 report (Form 10-K), filed with the SEC on February 26, 2026.
  • All figures are sourced from SEC EDGAR XBRL filings, last verified June 17, 2026.

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