Quick Answer
IONIS PHARMACEUTICALS INC reported Net Income of -$381.39 million for fiscal year 2025.
IONIS PHARMACEUTICALS INC Net Income — Annual History
| Fiscal Year | Net Income | YoY Change |
|---|---|---|
| 2025 | -$381.39M | +16.0% |
| 2024 | -$453.90M | -23.9% |
| 2023 | -$366.29M | -35.8% |
| 2022 | -$269.72M | -843.2% |
| 2021 | -$28.60M | +93.6% |
| 2020 | -$444.26M | -259.7% |
| 2019 | $278.14M | +1.6% |
| 2018 | $273.74M | +79015.9% |
| 2017 | $346.0K | +100.6% |
| 2016 | -$60.40M | +31.6% |
| 2015 | -$88.28M | -126.4% |
| 2014 | -$38.98M | +35.7% |
| 2013 | -$60.64M | +1.0% |
| 2010 | -$61.25M | -139.5% |
| 2009 | $155.07M | +953.3% |
| 2008 | -$18.17M | — |
Quarterly Net Income
| Quarter Ending | Net Income | YoY | QoQ |
|---|---|---|---|
| September 30, 2025 | -$128.61M | +8.5% | -204.1% |
| June 30, 2025 | $123.55M | +286.4% | +184.1% |
| March 31, 2025 | -$146.94M | -2.9% | -4.6% |
| September 30, 2024 | -$140.48M | +4.7% | -112.0% |
| June 30, 2024 | -$66.27M | +22.3% | +53.6% |
| March 31, 2024 | -$142.80M | -14.9% | +3.1% |
| September 30, 2023 | -$147.41M | -213.7% | -72.8% |
| June 30, 2023 | -$85.29M | +18.9% | +31.4% |
- IONIS PHARMACEUTICALS INC showed an increase of +16.0% in Net Income compared to the prior fiscal year.
- Over the 2008–2025 period, IONIS PHARMACEUTICALS INC’s net income has declined by 1998.8% (from -$18.17 million to -$381.39 million).
- The most recent figure is from IONIS PHARMACEUTICALS INC’s fiscal year 2025 report (Form 10-K), filed with the SEC on February 26, 2026.
- All figures are sourced from SEC EDGAR XBRL filings, last verified June 17, 2026.
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