Quick Answer
LEXICON PHARMACEUTICALS, INC. reported Operating Income of -$48.91 million for fiscal year 2025.
LEXICON PHARMACEUTICALS, INC. Operating Income — Annual History
| Fiscal Year | Operating Income | YoY Change |
|---|---|---|
| 2025 | -$48.91M | +75.2% |
| 2024 | -$197.12M | -14.8% |
| 2023 | -$171.75M | -70.5% |
| 2022 | -$100.76M | -15.7% |
| 2021 | -$87.09M | -82.2% |
| 2020 | -$47.80M | -133.8% |
| 2019 | $141.44M | +237.0% |
| 2018 | -$103.28M | +20.9% |
| 2017 | -$130.62M | -2.7% |
| 2016 | -$127.17M | -8762.9% |
| 2015 | $1.47M | +101.5% |
| 2014 | -$100.37M | +2.0% |
| 2013 | -$102.37M | +5.6% |
| 2012 | -$108.42M | +5.0% |
| 2011 | -$114.09M | -19.2% |
| 2010 | -$95.72M | -6.4% |
| 2009 | -$89.96M | — |
Quarterly Operating Income
| Quarter Ending | Operating Income | YoY | QoQ |
|---|---|---|---|
| September 30, 2025 | -$12.19M | +80.9% | -426.2% |
| June 30, 2025 | $3.74M | +106.7% | +114.5% |
| March 31, 2025 | -$25.68M | +43.4% | +59.7% |
| September 30, 2024 | -$63.69M | -28.3% | -15.1% |
| June 30, 2024 | -$55.35M | -25.1% | -22.1% |
| March 31, 2024 | -$45.33M | -45.6% | +8.7% |
| September 30, 2023 | -$49.63M | -114.9% | -12.2% |
| June 30, 2023 | -$44.24M | -84.3% | -42.1% |
- LEXICON PHARMACEUTICALS, INC. showed an increase of +75.2% in Operating Income compared to the prior fiscal year.
- Over the 2009–2025 period, LEXICON PHARMACEUTICALS, INC.’s operating income has grown by 45.6% (from -$89.96 million to -$48.91 million).
- The most recent figure is from LEXICON PHARMACEUTICALS, INC.’s fiscal year 2025 report (Form 10-K), filed with the SEC on March 5, 2026.
- All figures are sourced from SEC EDGAR XBRL filings, last verified June 17, 2026.
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