OnKure Therapeutics, Inc. Operating Income

Quick Answer

OnKure Therapeutics, Inc. reported Operating Income of -$62.95 million for fiscal year 2025.

OnKure Therapeutics, Inc. Operating Income — Annual History

Fiscal Year Operating Income YoY Change
2025 -$62.95M -15.7%
2024 -$54.39M -47.3%
2023 -$36.93M +31.4%
2022 -$53.85M -35.2%
2021 -$39.82M -103.7%
2020 -$19.55M

Quarterly Operating Income

Quarter Ending Operating Income YoY QoQ
September 30, 2025 -$15.50M -34.7% +5.0%
June 30, 2025 -$16.32M -13.8% +4.0%
March 31, 2025 -$17.00M -72.9% -47.7%
September 30, 2024 -$11.51M +44.9% +19.7%
June 30, 2024 -$14.34M +31.8% -45.9%
March 31, 2024 -$9.83M +39.0% +52.9%
September 30, 2023 -$20.89M -50.9% +0.7%
June 30, 2023 -$21.04M -69.2% -30.5%
  • OnKure Therapeutics, Inc. showed a decrease of -15.7% in Operating Income compared to the prior fiscal year.
  • Over the 2020–2025 period, OnKure Therapeutics, Inc.’s operating income has declined by 222.0% (from -$19.55 million to -$62.95 million).
  • The most recent figure is from OnKure Therapeutics, Inc.’s fiscal year 2025 report (Form 10-K), filed with the SEC on March 12, 2026.
  • All figures are sourced from SEC EDGAR XBRL filings, last verified June 17, 2026.

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