Quick Answer
Upstream Bio, Inc. reported Net Income of -$143.44 million for fiscal year 2025.
Upstream Bio, Inc. Net Income — Annual History
| Fiscal Year | Net Income | YoY Change |
|---|---|---|
| 2025 | -$143.44M | -128.4% |
| 2024 | -$62.81M | -205.8% |
| 2023 | -$20.54M | — |
Quarterly Net Income
| Quarter Ending | Net Income | YoY | QoQ |
|---|---|---|---|
| September 30, 2025 | -$33.75M | -111.0% | +15.6% |
| June 30, 2025 | -$39.97M | -172.3% | -46.6% |
| March 31, 2025 | -$27.27M | -150.3% | -70.5% |
| September 30, 2024 | -$15.99M | -415.5% | -9.0% |
| June 30, 2024 | -$14.68M | -477.9% | -34.7% |
| March 31, 2024 | -$10.89M | -255.8% | -251.2% |
| September 30, 2023 | -$3.10M | — | -22.1% |
| June 30, 2023 | -$2.54M | — | +17.0% |
- Upstream Bio, Inc. showed a decrease of -128.4% in Net Income compared to the prior fiscal year.
- Over the 2023–2025 period, Upstream Bio, Inc.’s net income has declined by 598.5% (from -$20.54 million to -$143.44 million).
- The most recent figure is from Upstream Bio, Inc.’s fiscal year 2025 report (Form 10-K), filed with the SEC on March 26, 2026.
- All figures are sourced from SEC EDGAR XBRL filings, last verified June 17, 2026.
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